Extracorporeal blood oxygenation and ozonation: clinical and biological implications of ozone therapy
Di Paolo N, Gaggiotti E, Galli F. Redox Report, 2005.
- Study type
- Narrative review
- People studied
- No participants of its own (narrative review)
- Published
- 2005, Redox Report
- Identifiers
- PMID 16156950, DOI 10.1179/135100005X38888
What the authors reported
Describes the EBOO technique (continuous extracorporeal filtration plus oxygen/ozone exchange) and argues it delivers a more controlled ozone dose to a larger blood volume than major autohemotherapy.
What limits this result
Narrative review authored by the technique's developers; presents rationale and early observations rather than new controlled outcome data.
Research on the procedure itself. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
Does EBO2 (EBOO) Work? An Honest Read of the Evidence
Does EBO2 (EBOO) work? Every published EBOO study, what ozone therapy generally shows, and why clinic testimonials are not the same as evidence.
EBO2 (EBOO) Therapy Cost in 2026: What US Clinics Charge
What EBO2 (EBOO) therapy costs at US clinics in 2026: sourced prices from eight clinics in five states, how packages work, and why insurance does not cover it.
EBO2 (EBOO) vs 10-Pass Ozone and MAH: What Is Actually Different
How EBO2 (EBOO), 10-pass ozone, and major autohemotherapy differ in blood volume, filtration, cost, and what the evidence actually supports.
EBO2 (EBOO) vs Plasmapheresis: Similar Machines, Very Different Medicine
EBO2 (EBOO) and plasmapheresis both draw blood through a machine and return it, but only one is an FDA-regulated therapy with graded indications.
The History of EBO2 (EBOO): From Bocci's Lab to Today's Wellness Clinics
How EBO2 (EBOO) developed from 19th-century ozone chemistry through Bocci's lab in Siena to today's US wellness clinics, with dates as documented in sources.
How Many EBO2 (EBOO) Sessions Do You Need? What Clinics and Studies Say
What the published EBOO studies actually used, what US clinics recommend as a series, and how to weigh a single session against a longer course.
What Is EBO2 (EBOO) Therapy? Procedure, Evidence, Cost, and Safety
A neutral, sourced explainer of EBO2 (also called EBOO): how the procedure works, what the research shows, typical cost, and the FDA's position.
What Does the EBO2 (EBOO) Filter Actually Remove?
EBO2 (EBOO) clinics say the filter removes toxins, cholesterol, and heavy metals. Here is what the device's pore size allows and what has been measured.
What to Expect During an EBO2 (EBOO) Session, Step by Step
A step-by-step walkthrough of an EBO2 (EBOO) session: intake, IV placement in both arms, what the circuit does, and what patients commonly report feeling.








