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Medical disclaimer

Effective September 25, 2026. Last updated October 6, 2026.

This disclaimer explains what the information on ebo2.com and app.ebo2.com is, and what it is not. It is part of our terms of use. It covers everything on both sites: the guides, the research library, the clinic directory, the reports and tools, the downloadable data, and anything we write to you. Please read it before you use anything here in a decision about your health.

No medical advice and no doctor-patient relationship

EBO2.com and app.ebo2.com give general information about EBO2 and related topics for education only. Nothing on either site is medical advice, a diagnosis, or a treatment recommendation. Nothing here tells you whether EBO2 is right for you, whether you can safely have it, or how many sessions you should have. That includes the reports, the tools, and the downloadable data: the price check compares a quote with the prices clinics publish, the session cost planner adds up costs, the clinic finder measures distance, and the questions for your doctor turn situations our guides describe into questions, without answering them. None of them weighs your health. The section on the tools, reports, and downloadable data says more.

Reading the sites, creating an account, or contacting us does not create a doctor-patient or other clinician-patient relationship with EBO2.com or with anyone who writes, checks, or reviews content for us. A "Medically reviewed by" line on a guide means that the licensed clinician named there reviewed that guide; it does not mean that anyone has evaluated you. No guide carries that line yet. We cannot give individual medical advice, including through the contact form, and we do not answer questions about your own symptoms, test results, or medications. Talk to your own clinician before you start, stop, or change any treatment, and do not delay care or set aside professional advice because of something you read here.

Emergencies

If you think you or someone with you may be having a medical emergency, call 911 in the United States or your local emergency number elsewhere, or go to the nearest emergency room. Do not search this site, wait for a reply from us, or wait for a clinic to call back. Our contact form is answered by people, usually within two business days, and it is not a way to get urgent help.

Situations that need emergency care

Call 911 for any of these, whether or not they follow a treatment of any kind:

Case reports in our research library describe deaths, strokes, heart attacks, a seizure, serious infections, and a heart rhythm problem called sinus arrest during or after other forms of ozone therapy. Those reports concern other ozone methods, not EBO2, but they show why signs like these call for emergency care rather than waiting to see whether they pass.

If you are in crisis or have been exposed to ozone

If you are thinking about suicide or harming yourself, call or text 988 to reach the 988 Suicide and Crisis Lifeline in the United States. If someone has breathed in ozone gas, for example from a home ozone generator, and has mild symptoms such as coughing or a sore throat, Poison Control at 1-800-222-1222 can advise you. If they have any trouble breathing, call 911.

Signs to report the same day

Some problems are not emergencies but should not wait. Our side effects and safety guide describes the signs its sources give as reasons to call a clinician after a procedure with a needle in a vein, such as redness, swelling, warmth, or pus at the needle site, or a fever. If you feel unwell during a session, tell the staff at once. Before a first session, ask the clinic how to reach someone after hours and what its plan is if a patient becomes unwell.

What "FDA approved," "cleared," "registered," and "compliant" mean

Clinic websites often use FDA words loosely. These four terms mean different things, and only approval means that the FDA has reviewed evidence that a product is safe and effective for a use. The definitions below come from the FDA's own regulations and consumer pages. Each source is also a record in our regulatory tracker, with its key words quoted.

Approved

For the highest-risk medical devices, the FDA generally requires approval of a premarket approval application before the device is sold, and the maker must show "a reasonable assurance that the devices are safe and effective for their intended uses" (FDA, Is It Really 'FDA Approved'?). Approval is for a specific product and specific uses. No EBO2 or EBOO device or protocol is FDA-approved to treat any condition, and federal regulation describes ozone itself as having no known useful medical application, as the next section explains.

Cleared

Many moderate-risk devices reach the market through what the FDA calls "510(k) clearance": the maker shows that its device is substantially equivalent to one already legally on the market. The FDA names "dialysis equipment" as an example of this kind of device. Clearance is not approval. FDA rules say that a statement creating "an impression of official approval of a device because of complying with the premarket notification regulations is misleading" (21 CFR 807.97). A clearance also names the use it covers. The regulation for high permeability hemodialysis systems, for example, describes them as "intended for use as an artificial kidney system for the treatment of patients with renal failure, fluid overload, or toxemic conditions" (21 CFR 876.5860). When a clinic says its equipment is "FDA-cleared," ask which part was cleared, and for what use.

Registered

Registration means that a company has told the FDA about a facility and listed the devices made or handled there. It is not a review of any product. Federal regulation says registration "does not in any way denote approval of the establishment or its products" (21 CFR 807.39), and the FDA explains that the resulting database entry "does not denote approval, clearance, or authorization of that facility or its medical devices" (FDA, Are There "FDA Registered" or "FDA Certified" Medical Devices?). The same page says the FDA does not issue registration certificates, so a certificate shown on a website is not an FDA document.

Compliant

We have not found "FDA compliant" defined in any FDA regulation or consumer page we have read, and we do not treat it as an FDA status. A company that uses the phrase may mean that it follows some FDA requirements, such as registering a facility or following manufacturing rules. The FDA says it inspects facilities to check that they follow those rules, but that it "does not approve manufacturing facilities independently" (FDA, Is It Really 'FDA Approved'?). Following a rule about how a device is made says nothing about whether a procedure is safe or effective for any use. If a clinic calls its equipment or protocol "FDA compliant," ask which requirement it means and for the document that shows it.

What the FDA has said about ozone and EBO2

Ozone

Federal regulation states: "Ozone is a toxic gas with no known useful medical application in specific, adjunctive, or preventive therapy" (21 CFR 801.415). The same section says that ozone strong enough to kill germs is far stronger than people and animals can safely tolerate, and it limits how much ozone a device may add to the air of rooms where people spend long periods, to 0.05 part per million. Our guides cite this regulation because it is the FDA's standing position on medical ozone. The guide Is EBO2 FDA approved? sets it out in full.

EBO2 equipment

On July 7, 2025, the FDA's Center for Biologics Evaluation and Research sent a warning letter to O3UV, LLC about two autohemotherapy devices, Champion Full Spectrum and EBOO Full Spectrum UV, which expose blood to ozone and ultraviolet light. The FDA said the devices were adulterated "because you do not for these devices have approved applications for premarket approval (PMA) in effect," and misbranded because the firm had not submitted a premarket notification. The letter also records that the EBOO kits included hemodialyzer filters bought from a supplier. Read the warning letter or our record of it. A warning letter states the agency's position on the date it was sent. It is not a court ruling, and the company may have responded since.

Health claims

In 2020 the FDA and the Federal Trade Commission warned clinics that promoted ozone therapy, among other treatments, for COVID-19. The FTC told one clinic: "We have determined that you are unlawfully advertising that certain services treat Coronavirus Disease 2019 (COVID-19)" (FTC warning letter, April 2020). The FDA keeps a list of fraudulent COVID-19 products. The same year, a Dallas health center agreed to a permanent injunction barring it from representing that ozone could be used to treat or cure COVID-19 (Department of Justice). The regulatory tracker lists these and other records from the FDA, the FTC, state boards, courts, and regulators abroad.

What we say and do not say

We report what these documents say, with their dates. We do not say that any clinic in our directory is breaking the law, that a device a clinic uses is one named in a warning letter, or that a clinic is safe or unsafe. When we describe what a clinic says or what a study found, that description is not a claim that EBO2 is safe or effective for any use. What a regulation means for a particular clinic or patient is a legal question; for that, ask a lawyer licensed where you live.

How strong the evidence is

Our research library holds 6 published papers on EBOO as given to people: 2 case reports, 2 case series, 1 randomized controlled trial, and 1 review. The largest enrolled 28 people. Most of this work comes from the group that developed the technique, and no large, independent, randomized trial has been published. The rest of the library covers other ozone methods, harms reported after ozone therapy, and laboratory science. Here is what each kind of evidence can and cannot tell you.

Case reports and studies without a comparison group

A case report describes one patient, and a case series a group of patients who all had the treatment. Without a comparison group that did not receive the treatment, a study cannot separate the treatment's effect from the natural course of an illness, the placebo effect, other treatments given at the same time, or the way symptoms often ease after a bad spell. Studies like these can raise questions worth testing. They cannot show that a treatment works.

Laboratory and animal studies

Studies of blood in a tube, of saline pumped through a device, or of animals show what happens under those conditions. Studies that measure markers in the blood show that a number changed, not that patients felt better or lived longer. Our library groups these as background science, with the note that none of them shows whether EBO2 helps patients.

Other ozone methods are not EBO2

Clinics often cite studies of other ozone methods, such as major autohemotherapy, in support of EBO2. A result for one method does not transfer automatically to another, because the dose, the route, and the amount of blood treated differ. We group those studies separately so that you can see which method each one tested.

What a summary can lose

Our notes on each study, and the structured study card on each study's page and in our downloadable data, record what the paper reports, in its own words where we quote it. A summary still leaves things out: how patients were chosen, who dropped out, how outcomes were measured, every side effect, and who paid for the work. Of the 78 study cards, 38 were read from the abstract alone because we could not read the full text, and each card says which it was. Read the original paper, and talk it over with a clinician, before you rely on it.

A small study can miss rare harms

A study of a few dozen people is too small to detect uncommon side effects, so a study that reports no serious harm does not show that a procedure is safe. The safety studies in our library and our side effects and safety guide describe the harms that have been reported.

The clinic directory is not an endorsement or a licensing check

A clinic appears in our directory because public sources or the clinic itself indicate that it offers EBO2 or EBOO. Each listing reports what the clinic says on its own website. A listing is not an endorsement, referral, recommendation, or ranking, and no clinic pays to be listed or placed higher.

What "Verified" and the dates mean

"Verified" means that on the date shown we confirmed, on the clinic's own website, that it offers EBO2 or EBOO, and the listing links to that page. "Last checked" is the last date we reviewed the listing. Where a listing shows what the clinic says about its service, such as a price or a session length, "Read on" gives the date we read those pages. Verification covers one fact on one date. It does not cover the clinic's licenses, inspections, safety record, complaint history, results, or prices, and it does not tell you whether the clinic still offers EBO2 today.

"Not stated on the pages we read"

When a listing says a fact is "Not stated on the pages we read," it means only that the clinic's pages we read did not state it. It does not mean that the clinic does not do it, or that it is hiding anything. Where we could not read a clinic's pages at all, the listing says so instead, and we never treat that clinic as not stating something.

Check before you book

When a listing names practitioners, it repeats the names and credentials the clinic publishes; we have not confirmed that those people hold a license. Before you book, confirm the services, the price, and who will treat you, and look up that person's license on your state's medical or nursing board website. Most boards offer a free license search. Our guide how to choose an EBO2 clinic lists more checks.

Prices

When we show a price, it is the price a clinic publishes on its own website for one session or a package, as of the date shown, with a link to the page it came from. It may not include a consultation, lab tests, add-ons, travel, or taxes, and the clinic may have changed it since. A price on our sites is not an offer from us or from the clinic, and we do not set, negotiate, or guarantee any price.

Our reports and the price check compare figures only with prices that clinics publish, and they say how many prices each comparison rests on. Many clinics do not publish a price, so the ones that do may not be typical. Before you pay, ask the clinic for a written quote that lists everything included, and ask what happens if you stop partway through a package.

Every count, share, median, and range of published prices on our sites, whether on the home page, in a report, a guide, or a tool, or on a state, city, or clinic page, is built from one set of prices: only clinics whose EBO2 page we could read are counted, and a clinic counts as publishing a price when that page states a price for a single session, in words we saved and checked. A price we recorded from a clinic's website when we checked its listing is outside that set. It can still appear on the clinic's own page and in the clinic data files, labeled by its source, and in the clinic finder, which marks it "From" and includes it when you filter for clinics with a price. It is never part of the counts, shares, medians, or ranges above. Our editorial policy explains the rule.

The tools, reports, and downloadable data

Our tools, reports, and downloadable data are built from the same records as the rest of the sites, and everything on this page applies to them. This section adds what is particular to each.

Information, not advice

The tools compare, add up, measure, and ask. The price check places a quote among the prices clinics publish. The session cost planner adds up the numbers you enter. The clinic finder lists the clinics in our directory by straight-line distance. The questions for your doctor turn the situations you check into questions for your own doctor, built only from situations our guides state with a cited source. We compiled that list from our guides and the sources they cite; a human editor has not yet checked it against those sources, and it has not yet been clinically reviewed. No tool scores you, ranks clinics, warns you off, or says whether you can or should have EBO2, and checking a box in the questions tool is not a screening.

Not a quote or an offer

A price in a report, a tool, or a data file is the price a clinic published on its own website on the date shown. It is not a quote, and it is not an offer from us or from the clinic. The planner's total is an estimate from the numbers you enter, not a bill. When the price check says that a quote is in the middle half of published prices, it is describing where a number falls, not saying that the quote is fair or that the treatment is worth it. A lower price is not a safer treatment, and a higher one is not a better one.

What the figures rest on

Each report and tool says how many clinics or studies a figure rests on and when the data was read. When fewer than 5 clinics publish a figure, we list the values instead of giving a median, and the price check does not place a quote at all. The clinics we list are not a random sample of the country. Counts of how clinics word the FDA status of EBO2, or of the health benefits their pages state, are counts of statements on their websites, not findings about any clinic, and a statement on a clinic's page is a claim, not evidence.

Distance is not suitability

The clinic finder measures straight lines between two approximate points: the middle of a ZIP code, or the position your browser reports, and a clinic's map point. It does not know driving distance, opening hours, or whether a clinic will treat you. A short distance, like a listing or a "Verified" label, is not a recommendation, and the finder cannot show clinics that we do not list.

The downloadable data

The files on our data page record what clinics, papers, and regulators stated, as we read them on the dates given. They can contain errors, they go out of date, and a copy you download does not update itself. They are offered under the CC BY 4.0 license, without warranties of any kind. They are not medical advice, and they do not rate or recommend any clinic. If someone else republishes or analyzes them, the conclusions are theirs, and their use does not mean that we, or any clinic in the data, endorse them. Our terms of use explain the license and what it does not cover.

No testimonials, and why

Our guides and clinic listings do not include testimonials, patient reviews, ratings, success stories, or before-and-after accounts, and we accept no payment for testimonials or for any other coverage. One person's account cannot be checked, and it cannot separate a treatment's effect from the natural course of an illness, the placebo effect, or other treatments taken at the same time. Clinics choose which stories to publish, so the ones you see are not a fair sample of everyone treated.

When a guide mentions that clinics publish testimonials, it does so to describe how clinics market the procedure, not as evidence that it works. Our research pass records whether a clinic's EBO2 pages show patient stories, but we do not show that on any listing or in our downloads. When comments become available on app.ebo2.com, a comment may describe its author's own experience. Each comment will be held for approval before it appears, but approval does not mean that we have checked it or agree with it.

Individual results vary

People respond differently to any treatment. How a person responds, including whether they have side effects, can depend on their health, their medications and other treatments, the clinic, the equipment, and the protocol used, and published protocols differ in ozone dose, the amount of blood treated, and the number of sessions. Nothing on the sites predicts or promises an outcome for you. An outcome reported in a study describes the people in that study, who may differ from you in age, health, and diagnosis. An outcome a clinic reports is the clinic's own claim, which we label as clinic-stated. Neither tells you what will happen in your case.

Content ages, and how we date it

Research changes, regulators revise their positions, and clinics change their services, staff, and prices. Every kind of page shows a date so that you can judge how current it is:

Our listing procedure calls for a recheck of every listing that reaches 90 days since its last check. The site's build also stops with an error if any listing goes more than 180 days without a check, so no new version of the site can be published until that listing is rechecked or removed. Even so, a page can be out of date the day after we check it. We cannot promise that any page is complete, current, or free of errors, so confirm anything important with its source. Our editorial policy explains how we choose sources, recheck listings, and correct mistakes.

Conflicts of interest

EBO2.com is not owned by, funded by, or affiliated with any clinic, device maker, or ozone-therapy trade group. We run no ads, use no affiliate links, sell no placement or badges, and accept no payment for coverage or for testimonials. Listings are free. The sites are paid for by their operator, and nothing on them is paid for by anyone we write about.

If that ever changes, for example if we offered a paid feature for clinics, we would first say so in our terms and our editorial policy, and we would label the paid feature wherever it appears. No payment would buy a "Verified" badge or change what our guides say about a clinic or a treatment.

AI-assisted drafting and human checking

Our guides are drafted with AI writing tools from the sources they cite. A human editor has not yet checked every claim in every guide against its cited source, and each guide says where its own review stands. We also use software, including AI research tools, to read clinic websites, published papers, and regulators' documents, and to copy out the exact words behind the facts we record about clinics' services and studies and the key words of each regulatory document. A script then checks that every recorded quote appears in the saved text of the pages read for that record, and that key numbers, such as prices, session lengths, and the sizes of study groups, appear in their quotes.

AI tools can misread a page or state something with more confidence than the source allows. That is why we keep the source's exact words, link every fact to its page, and correct errors when readers report them. No licensed clinician has reviewed any of our guides yet. Our editorial policy describes each step, and our medical review page explains what review will mean.

Third-party content and links

Our pages quote and link to material we do not control: clinic websites, journal articles on PubMed and publishers' sites, regulators' documents, and map services. A quote from a clinic's website is the clinic's own words, shown with a link to its page. Repeating it does not mean we agree with it or have checked that it is true. A paper's findings are its authors' claims. These pages can change or disappear after we read them, some papers sit behind a paywall, and a link can break when a site moves a page.

When you follow a link, you leave our sites, and the other site's terms and privacy policy apply. The map on a clinic page loads its tiles from OpenStreetMap. Tell us through the contact form if you find a broken link or a quote that no longer matches its page.

Who to talk to before treatment

Before you decide on EBO2 or any ozone therapy, talk to a licensed clinician who knows your health history and is not selling you the procedure. Depending on your situation, that may include:

Our contraindications guide describes the conditions clinics and practitioner groups commonly list. It can help you prepare questions, but it is not a screening, and not seeing your situation on a list does not mean the procedure is safe for you. Questions worth asking a clinic include who will be in the room during a session and what their licenses are, what happens before a first session, what the clinic does if a patient becomes unwell, what the whole course will cost, and what it tells patients about the evidence and the FDA's position.

How to report an error

If you find a mistake on any page, tell us through the contact form and choose "Report an error or request a correction." Each clinic listing also has a "Tell us" link that opens the same form. Please include the page address, what you believe is wrong, and, if you can, a link to a source that shows the correct information.

We check each report against the cited source, or against the clinic's own website for a listing. We correct substantive errors in our guides within five business days, update the page's date, and note material changes at the end of the guide. If we cannot confirm a change, we tell you and leave the page as it is until we can; if we disagree, we explain why. A clinic that wants to correct, claim, or remove its own listing can use the For clinics page.

Contact

Questions about this disclaimer: use the contact form or write to EBO2.com, 1968 S. Coast Hwy, #1921, Laguna Beach, CA 92651, United States. We cannot answer questions about your own health.

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