EBO2 (EBOO) Therapy Cost in 2026: What US Clinics Publish and What a Quote Leaves Out
What US clinics publish for EBO2 (EBOO): single-session and package prices from our dataset, fees a quote can leave out, and how to check package math.
EBO2 (EBOO) therapy, explained: how it works, what the research shows, and what clinics charge.
EBO2, also called EBOO, is a form of ozone therapy offered by some US wellness clinics. During a session, blood flows from a line in the arm through a filter, where it meets oxygen and ozone, and back through a second line.
We gather the published studies, what regulators have said, and what clinics state on their own pages, with a link to every source, so you can read it all in one place.
Where things stand
The research so far
We track 6 published papers on EBOO as given to people; 4 of them describe a single patient or a small series.
Safety
Any treatment that routes blood outside the body has known risks, which studies and regulators have recorded.
Does EBO2 (EBOO) Work? The Evidence, Study by Study
Every study in our EBO2 (EBOO) library in one place: design, size, what was measured and found, its limits, and a check for any study a clinic cites.
What 163 clinics say on their own pages
We read the EBO2 pages of 163 of the 177 listed clinics and recorded what each states, with the exact words and the page's address; clinics whose pages we could not read are left out of these counts. The latest reading was on September 28, 2026. These are counts of statements, not findings about any clinic.
24% publish a price for one session, 39 of 163. The median is $1,500. 94% name a condition or health benefit on their EBO2 page, 153 of 163. No EBO2 device is FDA-approved for any condition. 22 say EBO2 is not FDA-approved and 3 describe their equipment as FDA-cleared, registered, or approved. 138 of 163 say nothing about whether EBO2 or its equipment is FDA-approved.
What happens in a session
A clinic places two IV lines. A machine moves blood through a filter, where it meets a mix of oxygen and ozone across a membrane, and returns it. Clinics most often say a session takes 60 to 90 minutes.
- Blood is drawn from a vein in the arm.
- An anticoagulant and a pump keep it flowing without clotting.
- A filter exposes the blood to an oxygen and ozone mix across a membrane.
- Blood returns to the arm through a second line.
Clinics in 43 states
177 clinics listed. Verified listings link to the page on the clinic's own website where we confirmed it offers EBO2.
Questions people ask first
Every guide cites its sources and names the limits of each study.
What to Expect at an EBO2 (EBOO) Session: A Timeline From Clinic Pages and the Studies
An EBO2 (EBOO) visit stage by stage, from what clinic pages and the published studies say: intake and labs, preparation, the hour on the circuit, aftercare.
EBO2 (EBOO) Side Effects and Safety: What Studies, Case Reports, and Regulators Record
What the EBOO studies record about side effects, the harms documented with other ozone procedures, the risks of the circuit, and what regulators have found.
How to Choose an EBO2 (EBOO) Clinic: Checks You Can Run Before You Book
How to vet an EBO2 (EBOO) clinic: what clinic pages disclose, from our dataset, license and device lookups to run, what to get in writing, and 12 questions.
How this site works
- 740 cited sources across our guides. Clinical review of each guide is planned.
- No testimonials. Our articles and clinic listings do not include them, and we say plainly what the FDA has and has not approved.
- Free listings. No clinic pays for its listing or its position.
Read our editorial policy and medical review process.