EBO2 (EBOO) Therapy Cost in 2026: What US Clinics Publish and What a Quote Leaves Out
EBO2 (also called EBOO) is sold by US clinics as an out-of-pocket service, and most of them do not publish a price. This guide is built on what the clinics that do publish one show on their own pages: our dataset of 177 directory listings, each read and quoted, with the pages saved [19]. It answers three questions a reader with a quote in hand has: is this number in the usual range, what should it include, and does a package save money. To test a specific number, use the price check. To total a course with add-ons and travel, use the session cost planner. The full distribution is in the price report.
The short answer: as of October 4, 2026, 40 of the 174 clinics whose EBO2 pages we could read published a single-session price. The prices ran from $750 to $2,500, the median was $1,500, and the middle half fell between $1,274 and $1,550 [19]. Those figures are recomputed from the data each time the site is built, under “From our data” at the end of this page. For what the procedure is, see the pillar guide.
What do US clinics charge for one session?
Most clinics do not say. As of October 4, 2026, 134 of the 174 clinics whose EBO2 pages we could read publish no single-session price [19], and some, such as one Atlanta clinic, say the price is discussed at a first consultation [8]. The 40 published prices fall like this:
| Published single-session price | Clinics |
|---|---|
| Under $1,000 | 5 |
| $1,000 to $1,499 | 11 |
| Exactly $1,500 | 13 |
| More than $1,500 | 11 |
$1,500 is the most common figure by a wide margin: 13 of the 40 prices are exactly that, and 24 are $1,500 or more [19]. We count listings, not businesses: the 40 prices come from 36 websites, because four businesses list two locations at the same price. We count a price only when it was read on the clinic’s own EBO2 page; a price recorded in our directory before that page could be read is left out of every figure here, as it is from the blocks at the end of the page.
The prices do not support a comparison by state. They come from 17 states, and no state has more than 6 published prices, which is too few to say EBO2 costs more in one state than another. We also checked whether price tracked three things clinics state about the session: its length, a named device, and named clinicians. The median price in every one of those groups stayed within about $100 of $1,500, a difference too small to read anything into with 40 prices read from clinic pages [19].
What does a published price leave out?
A published price is often not the whole price. As of October 4, 2026, 26 of the 40 published prices came with at least one condition on the pages we saved [19]. A price can carry more than one:
| What the clinic’s pages say alongside the price | Prices |
|---|---|
| A separate consultation, evaluation, or first-visit fee | 9 |
| Several prices by protocol or version; our dataset records the base or lowest | 5 |
| The price covers a bundle (a consultation, lab orders, light or other therapies) | 4 |
| A lower price for members | 3 |
| A floor rather than a fixed price (“starting at”, “$850+”) | 4 |
| An optional add-on with its own price | 3 |
| Later sessions priced lower than the first (two listings of one clinic) | 2 |
| No statement of whether the price is per session or per series | 1 |
| Final price “confirmed at your consultation” | 1 |
| A lower rate for one group of patients | 1 |
An Arizona clinic charges $1,500 for the first session and $1,250 for each one after [11]. An Illinois clinic charges $1,500 to non-members and $1,200 to members [12]. A San Diego clinic charges $1,050 for EBOO and $1,250 for what it calls EBO2, which it defines as EBOO with a Hemealumen light device [2]. An Oregon clinic lists five protocols from $1,299 to $1,799 per treatment and requires a $100 consultation first [6]. When we read it on September 28, 2026, a South Carolina clinic’s $1,297 price was a package that included lab orders, a PEMF session, and light-therapy beds; its page now gives no price [13]. The number at the top of a pricing page answers only part of the question.
What should a quote itemize?
A consultation or evaluation fee
As of October 4, 2026, 10 of the 174 clinics whose pages we could read list a fee for a consultation, evaluation, or first visit before EBO2 somewhere on the pages we saved; the one-line intake statement we recorded for each clinic gives a fee for 5 of them [19]:
| Fee | What the clinic’s page says it is | Credited toward treatment |
|---|---|---|
| $50 | An “EBOO Establish visit” of up to 30 minutes for patients new to the clinic, which can be by phone [10] | Not stated |
| $100 | A required EBOO medical consultation [6] | Not stated |
| $100 | A medical pre-screen consultation required before any EBOO treatment, waived for members [20] | Not stated |
| $125 | An EBOO consultation, listed with the session fees [14] | Not stated |
| $150 | A 30-minute consultation [15] | Not stated |
| $150 | An optional phone consultation [4] | Yes, toward the first session |
| $250 | A one-time consultation, required for non-members [9] | Not stated |
| $250 | A medical evaluation that includes required lab tests and a physician consultation [7] | $150 toward a three-session package |
| $250 or $450 | A first consultation, at $450 for cancer patients [8] | Not stated |
| $600 | A 60-minute regenerative medicine consultation that reviews suitability for EBOO, which established patients may not need [21] | Not stated |
Other clinics describe a free consultation, such as a free 15-minute phone call at one South Carolina clinic [13], and one Texas clinic’s $1,500 first appointment covers both a half-hour consultation and the first session [5]. A quote that does not mention a consultation fee has not necessarily ruled one out.
Lab tests
Lab tests are mentioned far more often than they are priced. As of October 4, 2026, 33 of the 174 readable clinics mention lab tests, bloodwork, or biomarkers in the intake statement we recorded for each (what the clinic says happens before a first session), and 11 name G6PD, an enzyme test for the condition described under G6PD deficiency [19]. Few say who pays. One Texas clinic requires CBC, CMP, and G6PD results from the month before the appointment and offers to draw them for $20 [5]. Another folds its required labs into a $250 evaluation [7]. An Oregon clinic says a separate G6PD test is required before a protocol can be scheduled [6], a clinic near Austin lists G6PD, CMP, PT, PTT, and INR among its required labs [10], and a San Diego clinic says it may waive its lab requirement for CBC, CMP, and G6PD results from the past three months [2].
Add-ons
As of October 4, 2026, 22 of the 174 readable clinics list an add-on to EBO2, from 20 websites [19]. Two kinds recur:
- A light step, at 7 clinics: a Hemealumen light device named at 4, UV light at 2, and “extracorporeal photobiomodulation” at 1.
- An IV infusion, at 13 clinics on 11 websites: NAD+ at 4, glutathione at 7, methylene blue at 3, a Myers’ cocktail at 4, IV hydration at 2, and mentions of vitamin C, procaine, chelation, and an exosome infusion. As with prices, these are counts of listings: a business with several listings that name the same infusions counts once for each.
Single clinics also list PEMF and lymphatic drainage, PRP or stem-cell injections, other ozone therapies, before-and-after toxin testing, and supplements. Three clinics publish an add-on price: $90 for a Hemealumen light [5], $150 for UV light [4], and $300 for HemeaLumen added to any of four protocols [6]. Two more price the combination instead. A San Diego clinic’s EBO2 with the light device costs $200 more than its EBOO [2], and an Arizona clinic’s EBOO with NAD costs $201 more than EBOO alone, with EBOO plus procaine at $151 more [3]. Where a light step is priced, then, it adds $90 to $300 a session. A quote that includes a light device or an IV can be compared with other clinics only after the EBO2 price without it is known.
A deposit
Deposits carry their own terms. One Texas clinic takes a $700 deposit that is non-refundable if the appointment is cancelled within 3 business days [5]. A South Carolina clinic asks for a small deposit to reserve the day; on September 28, 2026, its page put it at $297 against a $1,297 package [13]. Another Texas clinic takes a $45 deposit toward its $250 evaluation, and its page says “All sales final” [7].
How do packages work, and when do they save money?
As of October 4, 2026, 17 of the 174 readable clinics publish a package price, from 15 websites, and together they list 21 packages [19]. Sixteen of the clinics sell a 3-session package, four a 5-session package, and one a 4-session package. Against the same clinic’s single-session price, the packages save a median of 10% per session, with a range of 0% to 17% and a middle half of 8% to 12%. Across a whole package that is $0 to $1,000, a median of about $500. Package totals run from $2,700 to $6,750.
The test that matters is what happens if a course stops early. In all 21 packages, the package total is more than the same clinic’s single price times one fewer session [19]. A 3-session package at $3,750 from a clinic that charges $1,500 a session comes to $1,250 a session if all three are used [1]. Stop after two, and those two cost $1,875 each, $750 more in total than two single sessions. The saving exists only for the buyer who uses every session.
Do the division rather than trusting the per-session figure printed beside a package. One Wisconsin clinic’s page lists “Three EBOO Sessions” at $3,750, described as $1,250 per session, and a second “Three EBOO Sessions” line at $5,000, described as $1,000 per session [1]. Divided by three, $5,000 is about $1,667 a session; it matches $1,000 per session only if that line means five sessions.
Refund terms are rarely published. Of the 17 listings with a package price, one page says “All sales final” [7], and none of the 17 pages we saved says whether unused sessions can be refunded, transferred, or will expire [19]. The answer, and whether the clinic will put it in writing, is worth having before any money changes hands. The how many sessions guide covers the separate question of what course length clinics recommend and what the studies used.
Why do prices differ between clinics?
The pages point to what is in the price more than to the procedure itself. Clinics with tiers charge more for protocols that add a light device or an infusion [2][3][6]. Clinics with memberships publish a lower member rate, $300 to $350 below the non-member price at the three that list both [12][19]. Bundles fold in consultations, lab orders, or other therapies [5][13]; our guide to what else clinics sell covers those services. A price with more inside it is not comparable, number for number, with a bare session price.
Every session also carries fixed costs. Two clinics cited here state that the filter (and, at one, the tubing) is single-use [6][7], and an FDA warning letter describes one maker’s “100 Pack EBOO Full Spectrum Kit” as including disposable hemodialyzer filters bought from a supplier [16]. The technique’s developers describe a session as about an hour of extracorporeal circulation treating up to 4,800 ml of heparinized blood [17], and as of October 4, 2026, the 101 clinics that state a session length give a median of about 75 minutes [19]. A lower-dose ozone method costs far less at clinics that offer both: one Wisconsin clinic lists a single major autohemotherapy session at $175 and a single EBOO session at $1,500 on the same page [1]. Our comparison with 10-pass ozone and MAH explains how the procedures differ.
None of this says whether a higher price buys a safer or better session. We have no data on outcomes by clinic, and none of the studies in our research library compares them.
Questions to ask about a quote
- Is the price for one session, and what does that session include?
- Is there a separate consultation, evaluation, or first-visit fee, and is it credited toward treatment?
- Which lab tests are required before the first session, who orders them, and who bills for them?
- Does the price include a light device, an IV infusion, or anything else, and what is the price without it?
- Is this the member or the non-member price, and what does membership cost?
- If the clinic sells several protocols, which one is this quote for, and what does each add?
- Is a deposit required, and when does it stop being refundable?
- For a package: what is the total, what happens to sessions not used, and can the clinic put that in writing?
- How long is the quoted price good for?
The price check places a quote against every published price, and the session cost planner adds fees, add-ons, and travel into an all-in total. Our guide to choosing a clinic covers the questions that are not about money, how to read a clinic’s EBO2 page decodes the FDA and benefit wording on pricing pages, and the clinic directory shows what each listed clinic states about its own service.
Does insurance, an HSA, or an FSA pay for it?
Ozone therapy is not FDA-approved for any condition, and the FDA’s device rules describe ozone as a toxic gas with no known useful medical application [18]. EBO2 is sold as an elective, cash-pay service; one Oregon clinic’s page, for example, says it does not bill insurance or provide superbills for it [6]. Our insurance guide sets out what clinics say about paying, what Medicare’s rules and the IRS publications on HSA and FSA spending say, and what we could not verify about insurers’ policies. For budgeting, the safe assumption is that the whole cost is out of pocket; an HSA or FSA changes how it is paid only if the plan administrator accepts the expense.
What we could not verify
- What the other 134 clinics charge. Clinics that publish no price quote it privately, and the 40 published prices may not represent them.
- Whether a published price is still current. Pages were read on the dates given below. Prices change: one clinic that showed a sale price (“was $1,500”) on September 28, 2026 shows no price at all now [13].
- What a membership costs. Three clinics publish member rates, but we did not capture membership fees, so we cannot say when a membership pays for itself.
- Packages outside the 21. Some pages state a discount without a total (“$500 off a three-session package”) [6] or price a program only in a sentence. Those are not in our package figures.
- Who pays for labs. Few pages say whether lab tests are billed by the clinic, by an outside lab, or through insurance.
- Refund and expiry terms. Almost none of the saved pages state them. A clinic may publish terms on a page we did not save.
- The Wisconsin package line. We could not tell from the page whether $5,000 buys three sessions or five [1].
- Whether price tracks quality or safety. We have no data that could show it.
How this guide was made
This guide rests on 21 sources: 17 clinic pages, cited only for what each clinic states about its own prices and fees; two FDA documents; one peer-reviewed review by the technique’s developers; and our own clinic dataset, which anyone can download. Every figure marked “As of October 4, 2026” was computed by a script from that dataset: 177 directory listings from 152 websites, all read between September 28, 2026 and October 4, 2026, of which 174 had EBO2 pages we could read with confidence. The qualifier, consultation-fee, add-on, and refund counts were classified by reading each saved clinic page. The figures in this guide and under “From our data” are computed from the same records whenever the site is built. Drafting used AI tools. A human editor has not yet checked this guide claim by claim against its sources, and no clinical reviewer has signed off yet. A price on this page is not a recommendation of any clinic.
From our data
What clinics publish for one session
Of 174 clinics whose EBO2 page we could read, 40 publish a single-session price. Those prices run from $750 to $2,500, and the median is $1,500. The middle half runs from $1,274 to $1,550.
The full price report and a tool to check a quote. Read between September 28, 2026 and October 4, 2026.
What clinics tell you before you book
Of 174 clinics whose EBO2 page we could read, this many:
The full report. Read between September 28, 2026 and October 4, 2026.
How many sessions clinics recommend and sell
Of 174 clinics whose EBO2 page we could read, 69 state a recommended course and 17 publish a package price.
Of the 69 that state a course, 48 give a number of sessions, from 1 to 15. The median of the smallest number each clinic names is 3, and of the largest is 6.
The package sizes are 3 sessions (16 clinics), 5 sessions (4 clinics) and 4 sessions (1 clinic).
A clinic's recommended course is its own advice, not a finding from a study. Read between September 28, 2026 and October 4, 2026.
Frequently asked questions
How much does one EBO2 session cost?
As of October 4, 2026, 40 of the 174 clinics whose EBO2 pages we could read published a single-session price. The prices ran from $750 to $2,500, the median was $1,500, and the middle half fell between $1,274 and $1,550. Most clinics publish no price at all: 134 of the 174 whose EBO2 pages we could read did not, and some say the price is set at a consultation.
Why do EBO2 prices vary so much between clinics?
Much of the spread is what the price includes. On clinics' own pages, some prices are starting-price figures, some are non-member rates with a lower member price, some are the base of several protocol tiers, and some bundle a consultation, lab orders, or light therapy. Where clinics price a light step separately, it adds $90 to $300 a session. We found no stated fact, such as session length or a named device, that separated higher prices from lower ones.
What should an EBO2 quote include?
The per-session price and what it covers; any consultation or evaluation fee and whether it is credited toward treatment; which lab tests are required and who bills for them; any add-on built into the price; the deposit and when it stops being refundable; and for a package, the total, the number of sessions, and what happens to sessions that are not used.
Are EBO2 packages worth it?
Only if every session is used. As of October 4, 2026, the 21 packages clinics published saved a median of 10% per session against the same clinic's single price, with a range of 0% to 17%. In all 21, the package total was more than paying the single price for one fewer session, so stopping early costs more than paying as you go.
Does insurance pay for EBO2?
We found no sign that it does. Ozone therapy is not FDA-approved for any condition, and EBO2 is sold as an elective, out-of-pocket service. Whether an HSA or FSA can pay is a question for the plan administrator. Our insurance guide sets out what clinics say about paying, what Medicare's rules and the IRS publications on HSA and FSA spending say, and what we could not verify about insurers' policies.
Is a cheaper EBO2 session a worse one?
Price tells us nothing we can measure about safety or effect. None of the studies in our research library compares outcomes by clinic or by price. A lower published price can also reflect a smaller bundle, a starting-price label, or a member rate, so comparing what each price includes says more than comparing the numbers.
Sources
- Ozone. Eden Healing Oasis (Green Bay, WI), 2026. Clinic-stated
- EBOO Ozone Therapy and EBO2 Therapy. San Diego Center for Restorative Medicine, 2026. Clinic-stated
- Extracorporeal Oxygenation & Ozoniation. Advanced IV Health (Tucson, AZ), 2026. Clinic-stated
- EBOO session pricing. SynergyO3 Medical (Encinitas, CA), 2026. Clinic-stated
- Extracorporeal Blood Oxygenation and Ozonation (EBOO) in San Antonio. O3 Plus Tx (San Antonio, TX), 2026. Clinic-stated
- Full-Spectrum EBOO Therapy in Lake Oswego, Oregon. Evergreen Factor (Lake Oswego, OR), 2026. Clinic-stated
- EBOO Therapy in The Woodlands, TX. Detoxity Holistic MediSpa (The Woodlands, TX), 2026. Clinic-stated
- EBOO Therapy. Progressive Medical Center (Atlanta, GA), 2026. Clinic-stated
- EBOO (Extracorporeal Blood Oxygenation and Ozonation). Burick Center (Mechanicsburg, PA), 2026. Clinic-stated
- EBOO IV Therapy in Marble Falls, Texas. Roots Integrative Medicine (Marble Falls, TX), 2026. Clinic-stated
- Ozone Therapy Specialist. Valley Spinal Care (Phoenix and Scottsdale, AZ), 2026. Clinic-stated
- EBOO Therapy. Vigeo Care Center & Aesthetics (Algonquin, IL), 2026. Clinic-stated
- EBOO Therapy in North Charleston. Charleston Pain Relief Center (North Charleston, SC), 2026. Clinic-stated
- EBOO Therapy. Infinity Hydration & Wellness (Muncy, PA), 2026. Clinic-stated
- Innate Healthcare Institute home page (consultation fee). Innate Healthcare Institute (Scottsdale, AZ), 2026. Clinic-stated
- Warning letter to O3UV, LLC (CBER 25-668840). U.S. Food and Drug Administration, 2025. Regulatory
- Extracorporeal blood oxygenation and ozonation: clinical and biological implications of ozone therapy. Redox Report (PubMed), 2005. Peer-reviewed Our notes on this study: Extracorporeal blood oxygenation and ozonation: clinical and biological implications of ozone therapy
- 21 CFR 801.415 Maximum acceptable level of ozone. eCFR (FDA), 2026. Regulatory
- EBO2 clinic dataset and the clinic pages it lists, read between September 28, 2026 and October 4, 2026. EBO2.com, 2026. Other
- EBOO Therapy. True Health DPC (Silverton, OR), 2026. Clinic-stated
- EBOO / EBO2 Therapy. Institute for Human Optimization (Hanover, MD), 2026. Clinic-stated