Oxygenation-ozonation of blood during extracorporeal circulation: in vitro efficiency of a new gas exchange device
Bocci V, Zanardi I, Travagli V, et al. Artificial Organs, 2007.
- Study type
- In vitro
- People studied
- No participants reported (laboratory study)
- Published
- 2007, Artificial Organs
- Identifiers
- PMID 17725702, DOI 10.1111/j.1525-1594.2007.00448.x
What the authors reported
Bench testing of a new hollow-fiber gas exchange device (L001) for EBOO, using a buffered saline solution containing KI rather than blood, showed efficient gas transfer with minimal foreign surface contact and negligible priming volume across the tested parameters.
What limits this result
In vitro test on a saline solution, not blood or patients, with no clinical outcomes; PubMed lists no study-design publication type, so "in vitro" is inferred from the described bench methodology; authored by the EBOO technique's developers.
How ozone acts on blood and cells, how blood filters work, the laboratory and device-development studies behind the EBOO circuit, and studies that measure markers in the blood rather than how patients fare. None of these shows whether EBO2 helps patients. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
How the study was done
- Design
- In vitro efficiency test of a new gas exchange device
- Setting
- Department of Physiology, University of Siena, Siena, Italy
- Read from
- Read from the abstract only; where this page says nothing about an item, the abstract does not report it. Read on September 28, 2026.
Source: Abstract on PubMed
Study arms
| Group | Participants | What they received |
|---|---|---|
| L001 gas exchange device (GED) | Not reported | Tested using a buffered saline solution containing KI, varying several parameters |
Source: Abstract on PubMed
What it measured
- Performance of the device in the saline solution containing KI
- Shown to be very versatile and efficient (no numeric results in the abstract)
The new GED has been tested by using a buffered saline solution containing KI and by varying several parameters, and it has shown to be very versatile and efficient.
- Main characteristics of the device
- Minimal foreign surface contact, high gas transfer, and negligible priming volume
Source: Abstract on PubMed
Where we cite this study
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