Extracorporeal blood oxygenation and ozonation (EBOO) in man. preliminary report
Di Paolo N, Bocci V, Garosi G, et al. International Journal of Artificial Organs, 2000.
- Study type
- Case report
- People studied
- Not reported
- Population
- Early human recipients of EBOO, including patients with atherosclerotic vasculopathy
- Published
- 2000, International Journal of Artificial Organs
- Identifiers
- PMID 10741810
What the authors reported
In the first human use of the EBOO apparatus, an author who self-tested the device noted disappearance of lipomas after six treatments; the device was then used in a patient with Madelung disease and several patients with atherosclerotic vasculopathy, with reported clinical benefit and no observed side effects.
What limits this result
Uncontrolled preliminary case series performed by the device's own inventors, including self-experimentation; no blinding, randomization, or precisely reported total sample size.
Research on the procedure itself. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
Does EBO2 (EBOO) Work? An Honest Read of the Evidence
Does EBO2 (EBOO) work? Every published EBOO study, what ozone therapy generally shows, and why clinic testimonials are not the same as evidence.
EBO2 (EBOO) vs Plasmapheresis: Similar Machines, Very Different Medicine
EBO2 (EBOO) and plasmapheresis both draw blood through a machine and return it, but only one is an FDA-regulated therapy with graded indications.
The History of EBO2 (EBOO): From Bocci's Lab to Today's Wellness Clinics
How EBO2 (EBOO) developed from 19th-century ozone chemistry through Bocci's lab in Siena to today's US wellness clinics, with dates as documented in sources.
How Many EBO2 (EBOO) Sessions Do You Need? What Clinics and Studies Say
What the published EBOO studies actually used, what US clinics recommend as a series, and how to weigh a single session against a longer course.
What Is EBO2 (EBOO) Therapy? Procedure, Evidence, Cost, and Safety
A neutral, sourced explainer of EBO2 (also called EBOO): how the procedure works, what the research shows, typical cost, and the FDA's position.




