Combining Ozonated Autohemotherapy with Pharmacological Therapy for Comorbid Insomnia and Myofascial Pain Syndrome: A Prospective Randomized Controlled Study
Shen W, Liu N, Ji Z, et al. Pain Research & Management, 2022.
- Study type
- Randomized controlled trial
- People studied
- 118 people
- Population
- Patients with comorbid insomnia and myofascial pain syndrome
- Published
- 2022, Pain Research & Management
- Identifiers
- PMID 37214227, DOI 10.1155/2022/3562191
What the authors reported
In a randomized trial of 118 patients, adding ozonated autohemotherapy to standard pharmacological therapy improved sleep quality, pain, and mood more than pharmacological therapy alone, with no adverse complications observed in either group.
What limits this result
Single-center trial without placebo control or blinding; safety was judged by observed complications rather than systematic adverse-event monitoring.
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