Clinical effectiveness of medical ozone therapy in COVID-19: the evidence and gaps map

Serra MEG, Baeza-Noci J, Abdala CVM, et al. Medical Gas Research, 2023.

View the abstract on PubMed

Study type
Narrative review
People studied
271 people, across the studies it reviews
Population
Patients across 13 pooled clinical studies of medical ozone therapy in COVID-19
Published
2023, Medical Gas Research
Identifiers
PMID 37077114, DOI 10.4103/2045-9912.372819
Group
Ozone therapy more broadly

What the authors reported

An evidence-and-gaps map of 13 clinical studies (271 patients total) on medical ozone therapy for COVID-19, mostly major or minor autohemotherapy or rectal insufflation in acute, often hospitalized infection.

What limits this result

Authored by ozone-therapy society members; maps existing acute-COVID studies rather than long COVID, and includes no EBO2-specific study.

Other ozone methods, such as major autohemotherapy, that clinics cite in support of EBO2. A result for one method does not transfer automatically to another. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.

Where we cite this study

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