Necrotizing fasciitis successfully treated with extracorporeal blood oxygenation and ozonization (EBOO)
Di Paolo N, Bocci V, Cappelletti F, et al. International Journal of Artificial Organs, 2002.
- Study type
- Case report
- People studied
- 1 person
- Population
- Dialysis patient with necrotizing fasciitis unresponsive to standard therapy
- Published
- 2002, International Journal of Artificial Organs
- Identifiers
- PMID 12518965, DOI 10.1177/039139880202501212
What the authors reported
A dialysis patient with necrotizing fasciitis who had not improved with traditional therapies improved radically after treatment with EBOO, which the authors describe as already used routinely at their hospital.
What limits this result
Single case report from the technique's own developers; no control patient, randomization, or blinding, and no long-term follow-up reported.
Research on the procedure itself. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
Does EBO2 (EBOO) Work? An Honest Read of the Evidence
Does EBO2 (EBOO) work? Every published EBOO study, what ozone therapy generally shows, and why clinic testimonials are not the same as evidence.
What Is EBO2 (EBOO) Therapy? Procedure, Evidence, Cost, and Safety
A neutral, sourced explainer of EBO2 (also called EBOO): how the procedure works, what the research shows, typical cost, and the FDA's position.

