Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders
Scassellati C, Galoforo AC, Bonvicini C, et al. Ageing Research Reviews, 2020.
- Study type
- Narrative review
- People studied
- No participants of its own (narrative review)
- Published
- 2020, Ageing Research Reviews
- Identifiers
- PMID 32810649, DOI 10.1016/j.arr.2020.101138
What the authors reported
A mechanistic review proposing that controlled, low-dose ozone activates the Nrf2 antioxidant pathway, and arguing this could be relevant to aging and neurodegenerative disease.
What limits this result
A hypothesis-generating narrative review, not a clinical trial; cites laboratory and animal mechanism data rather than a human outcome linking ozone exposure to slower aging.
How ozone acts on blood and cells, how blood filters work, and studies that measure markers in the blood rather than how patients fare. None of these shows whether EBO2 helps patients. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
EBO2 (EBOO) for Longevity and Anti-Aging: The Oxidative Preconditioning Idea
A sourced look at EBO2 (EBOO) for longevity: the oxidative preconditioning idea behind the marketing, and why no study yet ties it to lifespan.