Associations between particulate matter air pollutants and hospitalization risk for systemic lupus erythematosus: a time-series study from Xi'an, China
Pan Y, Fang Y, Chen Y, et al. Environmental Geochemistry and Health, 2023.
- Study type
- Other
- Published
- 2023, Environmental Geochemistry and Health
- Identifiers
- PMID 36287357, DOI 10.1007/s10653-022-01409-3
What the authors reported
A time-series study in Xi'an, China linked fine and coarse particulate matter with increased hospital admissions for systemic lupus erythematosus, while finding no significant association between ambient ozone (O3) and SLE admissions.
What limits this result
An ecological, population-level air-pollution study of ambient exposure, not any ozone therapy; cannot show what a controlled medical ozone exposure does in an individual patient.
Harms reported after ozone therapy, and studies of how ozone exposure affects health. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
How the study was done
- Design
- Time-series study of particulate matter air pollutants and hospitalization risk for systemic lupus erythematosus
- Setting
- Xi'an, China: SLE admission records from the First Affiliated Hospital of Xi'an Jiaotong University; air pollutant data from the Xi'an Environmental Monitoring Station
- Read from
- Read from the abstract only; where this page says nothing about an item, the abstract does not report it. Read on September 29, 2026.
Source: Abstract on PubMed
What it measured
- PM2.5 and PM10 exposure and risk of SLE admission (exposure-response curves)
- Positive associations
- PM2.5 exposure by subgroup
- Associated with increased risk of SLE admission in women, age over 65 years, and during the cold season
- PM10 exposure by subgroup
- Increased risk of SLE in women and during the cold season
- Tests between subgroups
- Additional tests did not observe significant associations of PM2.5 and PM10 exposure with SLE admission between subgroups
- Carbon monoxide, nitrogen dioxide, ozone (O3) and sulfur dioxide and risk of SLE admission
- Null associations were found
- Authors' conclusion
- PM2.5 and PM10 exposures have significant effects on the risk of SLE admission
Source: Abstract on PubMed
Funding and conflicts
Funding listed on PubMed: National Natural Science Foundation of China (82103932; 81872687), Anhui Provincial Natural Science Foundation (2108085QH361; 2108085Y26), Research Fund of Anhui Institute of Translational Medicine (2021zhyx-B04)
Source: Abstract on PubMed
Where we cite this study
Does EBO2 (EBOO) Work? The Evidence, Study by Study
Every study in our EBO2 (EBOO) library in one place: design, size, what was measured and found, its limits, and a check for any study a clinic cites.
EBO2 (EBOO) for Autoimmune Conditions: Clinic Claims, the MS and Sjögren's Studies, and Standard Care
What clinics claim about EBO2 (EBOO) for autoimmune disease, what the MS, Sjögren's and RA ozone studies measured, and what NIH describes as care.