Therapeutic Effect of Medical Ozone on Lumbar Disc Herniation
Niu T, Lv C, Yi G, et al. Medical Science Monitor, 2018.
- Study type
- Randomized controlled trial
- People studied
- 80 people
- Population
- Patients with trauma-induced lumbar disc herniation
- Published
- 2018, Medical Science Monitor
- Identifiers
- PMID 29611536, DOI 10.12659/msm.903243
What the authors reported
In 80 patients randomized to control or low, medium (40 ug/mL), or high (60 ug/mL) concentrations of medical ozone, the medium concentration produced the greatest disc retraction and reduced inflammatory markers, while the highest concentration increased inflammatory marker expression instead of reducing it.
What limits this result
Single-center trial; the abstract does not describe blinding; biochemical and imaging surrogate endpoints are emphasized alongside clinical pain scores.
Other ozone methods, such as major autohemotherapy, that clinics cite in support of EBO2. A result for one method does not transfer automatically to another. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
What Is EBO2 (EBOO) Therapy? Procedure, Evidence, Cost, and Safety
A neutral, sourced explainer of EBO2 (also called EBOO): how the procedure works, what the research shows, typical cost, and the FDA's position.