Oxidative stress, antioxidants, hormesis and calorie restriction: the current perspective in the biology of aging

Mehdi MM, Solanki P, Singh P. Archives of Gerontology and Geriatrics, 2021.

View the abstract on PubMed

Study type
Review
People studied
No participants of its own (review)
Published
2021, Archives of Gerontology and Geriatrics
Identifiers
PMID 33845417, DOI 10.1016/j.archger.2021.104413
Group
Background science and mechanism studies

What the authors reported

A narrative review of how oxidative stress, antioxidant defenses, and hormesis (a low-dose stress producing a protective response) are theorized to shape biological aging.

What limits this result

A general biology-of-aging review with no mention of ozone or EBO2; describes hormesis as a broad concept, not evidence that any ozone procedure slows aging.

How ozone acts on blood and cells, how blood filters work, the laboratory and device-development studies behind the EBOO circuit, and studies that measure markers in the blood rather than how patients fare. None of these shows whether EBO2 helps patients. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.

How the study was done

Design
Review that emphasizes the theories of aging and the various levels of molecular damage by oxidative stress
Setting
Department of Biochemistry, School of Bio-engineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India (first author's affiliation)
Read from
Read from the abstract only; where this page says nothing about an item, the abstract does not report it. Read on September 28, 2026.

Source: Abstract on PubMed

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