SIOOT recommendations for the optimal application of the oxygen-ozone therapy in clinical medicine
Franzini M, Vaiano F, Tirelli U, et al. International Immunopharmacology, 2025.
- Study type
- Other
- Published
- 2025, International Immunopharmacology
- Identifiers
- PMID 39657536, DOI 10.1016/j.intimp.2024.113751
What the authors reported
A professional-society position paper arguing that oxygen-ozone therapy needs standardized protocols and physician training, stating that inconsistent practice currently limits safety, efficacy, and reproducibility across the field.
What limits this result
A recommendations and position statement from an ozone-therapy society (SIOOT), not a controlled study; reports no new patient outcomes or trial data of its own.
Other ozone methods, such as major autohemotherapy, that clinics cite in support of EBO2. A result for one method does not transfer automatically to another. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.
Where we cite this study
Who Should Not Get EBO2 (EBOO)? Contraindications and Precautions
The contraindications, relative precautions, and screening questions clinics commonly use for EBO2 (EBOO), and the reasoning behind each one.