Suspected Pulmonary Embolism after Oxygen-Ozone Therapy for Low Back Pain

Chirchiglia D, Chirchiglia P, Stroscio C, Volpentesta G, et al. Journal of Neurological Surgery Part A: Central European Neurosurgery, 2019.

View the abstract on PubMed

Study type
Case report
People studied
1 person
Population
Elderly woman treated with oxygen-ozone therapy for lumbar pain caused by disk protrusion
Published
2019, Journal of Neurological Surgery Part A: Central European Neurosurgery
Identifiers
PMID 31430795, DOI 10.1055/s-0039-1685197
Group
Safety and adverse events

What the authors reported

An elderly woman treated with oxygen-ozone therapy for lumbar pain from a disk protrusion had a suspected pulmonary embolism followed by sudden death. The authors believe a massive pulmonary embolism occurred, probably caused by an intradiskal injection that accidentally punctured a venous vessel and created emboli.

What limits this result

Single case report, read from the abstract only. The embolism is described as suspected and its cause as the authors' belief; the abstract gives no age beyond "elderly", no ozone dose or volume, and no timing, and does not say how the diagnosis was investigated.

Harms reported after ozone therapy, and studies of how ozone exposure affects health. One study rarely settles a medical question; our guides weigh each paper against the rest of the evidence.

How the study was done

Design
Case report (PubMed publication type)
Setting
Department of Neurosurgery, University of Catanzaro, Catanzaro, Italy (author affiliation)
Read from
Read from the abstract only; where this page says nothing about an item, the abstract does not report it. Read on October 2, 2026.

Source: Abstract on PubMed

Study arms

Each group as the paper describes it.
GroupParticipantsWhat they received
Single patient: elderly womanNot reportedOxygen-ozone therapy for lumbar pain caused by disk protrusion

Source: Abstract on PubMed

What it measured

Course after oxygen-ozone therapy
Suspected pulmonary embolism, followed by sudden deathWe describe a case of suspected pulmonary embolism, followed by sudden death, in an elderly woman treated with oxygen-ozone therapy for lumbar pain caused by disk protrusion.
Authors' explanation
A massive pulmonary embolism, probably caused by an intradiskal injection that accidentally punctured a venous vessel and created emboli

Source: Abstract on PubMed

Safety as reported

Suspected massive pulmonary embolism followed by sudden death, which the authors believe an intradiskal injection probably causedWe believe a massive pulmonary embolism occurred, probably caused by an intradiskal injection that accidentally punctured a venous vessel and created emboli.

Source: Abstract on PubMed

Funding and conflicts

Conflict of interest statement on PubMed: None

Source: Abstract on PubMed

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